When one snorts a line of oxycontin mixed with cocaine.
Oxycontin is a synthetic heroine that also acts upon the opiate receptors in the brain. The name is derived from speedball, a mixture of heroine and cocaine, and mimics the same effects. Caffeine is sometimes used in place of cocaine either with crushed pills or a simple espresso drink.
Some heavier users prefer the oxyball to the speedball because the drugs get out of the system quicker.
Conversely, oxyballs can be considered a "gateway drug" to speedballs, as the user feels he is not resorting to needles yet.
" Hey, I need that coke for an oxyball tonight."
"I was oxyballing on Saturday and got completely fubar."