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1.
To remove a leader or government from power, especially by force. To bring about a coup d'état.
The coup d'état had failed miserably. The queen exacted vengeance on the group who had plotted to overthrow her, beginning with her duplicitous former friend, the Duke of Leicester.

The Prime Minister and her Cabinet perished in the blast; the overthrow was underway.
by Loreleili February 04, 2011
28 9
 
2.
to drink alcohol
We will overthrow in the swamps and then go bowling.
by TeamBearCats July 10, 2008
1 13