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1.
Edge of a geographic area. The part or region remote from a central district, as of a city or town.
As a noun, plural form is much more commonly used.
Many people commute into the business district from the outskirts of town.
by Diesel316 May 23, 2008
 
2.
The outer portion of a woman's vagina; the labia minora
"I slipped my hand into her panties and she felt pretty wet at the outskirts."
by Rob Karnage June 13, 2006
 
3.
lesbians

women who are "out"
n. "us outskirts gotta stick together"

or

adj. "a few outskirt friends of mine are getting together later. Want to come?"

by ratdreams January 23, 2007