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Get out of your mind

To behave in a manner opposite of normal life resulting in any form of altered mental state, usually as a result of heavy consumption of alcohol. Behavior is akin to a semi truck with no fucking brakes. Inspired by the song of the same name, written and performed by the glorious, genius Lil Jon himself.
"Get out of your mind. Get out of your mind. Fuck that shit, get out of your mind."-Lil Jon

Are you out of your mind!? 

a phrase someone used when they're going insane,
i wanna dive in a pool 9 miles up in the sky!
Are you out of your mind!?

Are you out of your fucking mind? 

Something someone says when they are mad at or are stunned by person.

It is also something Dane Cook wants to say.
If someone was running into a burning building with bare feet, a person would say, "Are you out of your fucking mind?"

Are you out of your fucking mind? 

Me: Are you out of your fucking mind?
My retarded friend: Hamburger.

out of your cotton-picking mind 

A condition where you are not thinking properly. Not in your normal state, not working with your normal faculties. Out of your gourd, feeling crazy enough to do something you would never normally do. Generally considered to be related to the odd behavior of heat stroke victims or victims of exhaustion, conditions that people who would pick cotton for a living in very hot or very stressful conditions might end up suffering.
"What did you do THAT for? Are you out of your cotton-picking mind?"

"He's babbling like an idiot, like he's out of his cotton-picking mind."

out of your cotton-picking mind 

to say someone is crazy, a fool
When May and Mary went screaming and running crazily down the street, dad muttered, "You two are out of your cotton-picking minds."