Oswego State University - In up sate New York on the shore of Lake Ontario
OSU, Home of the Lakers
by Aaron Spencer August 08, 2006
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(usually pronounced: oos )

A term used in karate or mixed martial arts schools meaning yes, hello, goodbye, and I understand. A general affirmative.
Teacher: Is everybody ready?
Students: Osu!
Teacher: Begin!
by Guildenstern14 November 12, 2009
Ohio State University

The home of the 2002 Ohio State National Champions.
by James Carpenter March 19, 2003
osu! is a freeware rhythm game originally for Microsoft Windows. It is written in C# on the .NET Framework. The game has also been ported to Mac OS X, iOS, and Android. Its gameplay is based on commercial titles including Osu! Tatakae! Ouendan, Elite Beat Agents, Taiko no Tatsujin, beatmania IIDX, O2Jam, and DJMax.

Despite the stupidity stupidity of some; it is pronounced Oh-Sue. Not OOS.
A: Have you heard that game, osu?

M: Yeah it's like guitar hero except you pick the songs.

A: Wow sounds cool. How do I say it?

M: Oh-Sue.
by Oh-Sue September 06, 2014
A Japanese Word meant to show respect. It's used for evens like Karate before the fight.

"OSU" pronounced like "os".
Osu - Let the fight begin
by James Laserbeem August 26, 2005
Oregon State University, located in corvallis Oregon with branches in Portland, Albany, and Eugene. Its official colors are orange and black. as opposed to colors picked by UO, matching the color of their hippie weed accidently washed in with their white jersey.
2) School that jealous UO people and UO fans hate for its superior academics and athletics.
1)I went to UO instead of OSU because it was cheaper, there is no other logical reason.
2) I wish I had went to OSU because everything at UO is shit.
by [Sri] May 04, 2004
Oklahoma State University
OSU is a tight univeristy!
by Dizeb November 01, 2003
On stage urination. When someone who is on stage performing decides to urinate right there.
I didn't know Fergie liked OSU
by Amy Ger December 01, 2007

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