Top Definition
The process of befriending the best friend(s) of your best friend. Given the mutual common best friend, a relationship can easily be formed with your best friend's said best friend(s).
My best friend's friends came to visit this weekend. I instantly became best friends with them through the process of Osmosis Besties. We are now one group of real life Besties.
by KyFace September 28, 2009
5 Words related to osmosis besties

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