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1.
A phrase used largely by the gay community of Liverpool as a way of ascertaining the extent of a person's intoxication by either alcohol or drugs. Most commonly the latter. The 'she' refers to oneself in the third person. 'She' is used whether the subject is male or female.
"How are you doing? You look pretty wasted."

"Oh babe, she's not well!"
by Gazbags January 21, 2010