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1.
The altered mental state that accompanies acute illness or use of intoxicating substances. Usually a result of too many bevvies.
"I don't remember what happened last night, I was completely off my face."

"She got off her face and started slapping people."
by jessie4000 June 07, 2006
 
2.
When you get really drunk!
Yesterday night I was off my face at the bar!
by plinio_desce December 02, 2008