someone who is slightly less intellegant than the average person. this may range from being the last person to get a joke to someone who is mentally impared in some way.
you're such a nuffie, i cant believe you forgot to bring the popcorn!
by glamgirl June 25, 2006
a person not worth a damn; someone so stupid and insignificant that the sight of them actually angers you.
Oh my God, that blonde girl over there is such a fucking nuffie, I want to cunt punt her out of a window.
by lemule January 04, 2015