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2.
a dirty oral sex trick that involves a chick peeing on a dude when he goes down on her. gross, i know.
"Oh man, when I went down on LeKeesha last night, she noxzema-ed me. That dirty slut.
by Air Force Gopher February 11, 2005
 
1.
Facial cream
In 2009 NBA highlights, commentator yells "Dwayne Wade applying some Noxzema!!!! What a facial!"