A pain induced by either too much masturbation or via masturbating too many times in a 24 hour period. Usually results in an enlarged glans that throbs red, and not in the usual good way - it hurts!
1) I wanked so hard now I've got nob ache.
2) I came so much, no I've got nob ache
(Aus) A pain in the ass
He's no good, a fucking nob ache