2: a slang for drugs, such as weed, crack, heroine, etc.
3: an insult, closely related to jerk. usually insulting the person being called a nipplecube because of a negative or mean action.
2: man I got so wasted last night on nipplecubes, it was sweet.
3: I heard that guy dated 3 girls at the same time. what a nipplecube.