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2.
Generic term describing the pain/blister on your thumb from playing long sessions of video games.
After playing the new Mortal Kombat game for 12 hours straight, John had a seriously bad case of Nintendo Thumb.
by Apocalyptimaniac September 24, 2005
36 10
 
1.
A condition marked by blisters, which come after a long session of playing a video game. So named because the NES Controllers caused this condition frequently.
I beat Renegade, and all I have to show for it is a bad case of Nintendo thumb.
by Wadatah May 21, 2005
81 20
 
3.
The numbness of the thumbs and index fingers commonly occurring after hours of game console use.
"Those fucking Covenant sonofabitches are giving me nintendo thumb!"
by Keith November 29, 2003
24 11