Top Definition
A salutation (or greeting) typically uttered by an African American male to a friend or acquaintance who is a Caucasian. In this instance, the word "nilla" is an abbreviation for the word vanilla which refers to the Caucasian male's skin color.
What's up my nilla negro? (Pronounced: whazzup mah nilla neegro)
by parataxic_d May 29, 2006

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