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4.
In Spanish, and in many Spanish speaking countries, "nene" is a term of endearment used for males ("nena" for females).

It can be used toward each other amongst lovers, family, friends and even sometimes strangers in a joking or "light-hearted" manner, depending on the context and how its used in the Spanish speaking country of origin where the person saying it is from.

It can be equivalent to saying "honey", "hun", "sweetie", "babe", "baby", etc.
Wife: "How was your day at work nene?"
Husband: "Exhausting.. I'm tired and hungry. What's for dinner mami?"

Mom: "Hurry up and get ready for school nene. You're gonna be late!"
Son: "But I don't feel so good. I think I'm sick" *coughs*

Friend (guy): "Damn, look at Carmen.. She's so fly."
Friend (girl): "You still crushin' on her nene? Man, you've liked her since 6th grade! Why don't you just ask her out??"

Cash register older lady: "Find everything in the store ok nene?"
Kid: "Yes Ma'm"
by Mamisonga25 January 23, 2011
 
1.
a word a girl uses for her novio. it's like honey or baby.
i love my nene
by gaby June 28, 2004
 
2.
A little boy, or a hot guy.
You are a nene, I wanna be ya mamacita.
by Tono December 09, 2003
 
3.
The sweetest most gorgeous girl in the world! Friendly to all but keeps your deepest darkest secrets and never tells. Her long beautiful hair, rocking body, and model-like face turns the head of more than a few boys'. Her crazy personality draws many friends. Having a NeNe in your life makes everything perfect!
She's so perfect, she must be a NeNe!
by Frans4Lyf January 06, 2013
 
5.
A variation of neigh neigh. The accent is compulsory. Used to describe an American blonde girl, who is unique.
Boy 1: I think that hot girl over there is eyeing me up.
Boy 2: Totally! She is such a Né Né.
by ethanluke July 17, 2011
 
7.
Term of endeerment often used by weasly New Yorkeans (see El Piglet Royal)to attract young boys.
Hey, Nene, howz it goin?? How would youz like to come swimmin in my new pool??
by NOT Nene July 04, 2003