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1.
another way of writing/saying "nephew"

<another way is 'nephu'>
Dat's my lil nefu right dere!
by jgurl201 April 16, 2009
 
2.
A crazy person who strips down naked and pisses in front of an occupied police car.
Yo dawg, that guy just nefus'ed right in front of the quicky mart.
by ThatGuyWithTheMasses August 01, 2011