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1.
A nacho chip that holds the whole plate of chips together by interconnecting melted cheese... The nacho neclues is often found in the middle of the plate and when removed lifts every other chip up with it...
Mate.... I can't belive you just tried to pick up the nacho nucleus!
by Millwall George February 29, 2008
 
2.
The center part and main chip(s) of a bowl of nachos that holds all the nachos together. It contains the most chips, cheese and toppings in the whole bowl.
"Every pile of Nachos has one main chip that holds the whole thing together! The Nacho Nucleus! You don't take the Nucleus! You work around it!
...you honor it!" -Doug from the King of Queens.
by BGtheFiend July 29, 2014