The MySpace layout is basically the page design of your MySpace account. It is the page set up. The layout determines how your account page looks and where different links and profiles are located on the page. There are many different MySpace layouts available all over the web. Some layouts are given to you for free and some are not free. There are page layouts with themes available from "Retro" to "Girly" to anything else you can think of. The layouts are very easy to add onto your MySpace page. When you choose a layout on the web they will give you the code of that specific layout. All you have to do then is type that code into your profile box at the bottom of your MySpace page and it will upload.
Yeah, I just hooked my profile up with a new Justin Timberlake myspace layout.