Mute (noun) is a creature, most often human, who has been mutated by radiation and acuired monster-like properties, such as green skin, huge muscle growth, warts and disfigurations. This is usualy acompanied by lowered intelect, increased resilliance, and an intense hatred of people unnafected (see normies)
Fuckin' muties ain't gonna get in MY bomb shelter.
A movie, tv show or music video that is best watched on mute (ie. no volume). Often, this is for a video that is generally considered bad, but still contains lots of hot women. What you do when it's on mute, is your business :)