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1.
Muff Wagon orriginated when females decided to go "cruising" in their cars and search for guys. It is almost the opposite of a sausage fest; however, a sausage fest can occur at any place. A muff wagon is limited to a car full of dirty ho's who think they are hot, and do not keep their auzzie hair in order.
Hey dude, look at that muff wagon, its full of those crazy ho's we saw last night.
by Tink April 25, 2004
 
2.
A car or other form of transport which is being used by one or more attractive women.

As used in the popular British TV Show "The Inbetweeners".
*A car with four attractive women drives past*
Man1: Woah mate look at them!
Man2: Nice! That is one of the best Muff-Wagons I have EVER seen!
by Wye Knott October 02, 2010