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2.
means girl in french. Usually people say meuf but all the cool kids say mouff.
Cette mouff me fait trop chier
by geatredbird April 19, 2006
 
1.
Originally an ebonics term for "mouth", mouff has evolved to encompass one's entire being.
I want to hang out with your mouff tonight!
by iAmTheWhale January 10, 2008