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22.
A motherfucker can be known in the literal sense (by that I mean someone who has fucked your mother) but the true definition of a motherfucker is the following: a bad guy/ terrorist who means to bring evil into the world or just pisses Bruce Willis off.
"Yippee-ki-yay motherfucker" - Die Hard
"Yippee-ki-yay motherfucker" - Die Hard 2
"Yippee-ki-yay motherfucker" - Die Hard With A Vengeance
"Yippee-ki-yay motherfucker" - Die Hard 4.0/ Live Free or Die Hard
by Ewan JF December 24, 2009
 
23.
When you stubb your toe
" MU-th-aa FFFFuu-ccckk-errrrrrrr"
by Joey May 12, 2003
 
24.
Used to denote someone with whom you may have a personal problem.
"English, motherfucker, do you speak it?" -Samuel L. Jackson
by Mike McW October 22, 2007
 
25.
one of the most versatile words in the english language.
that motherfucking motherfucker stole fifteen motherfucking dollars from that motherfucker!!
by b-low July 24, 2006
 
26.
One who fucks his or her own mother. However, in recent times, it has adapted to:

1.) One who fucks any mother (which means your father/mother's girlfriend is a motherfucker).

2.) An adaptable insult for anyone whom you'd like to offend.
1.) "Johnny, you're such an incestuous pig, you motherfucker!"

2.) "Your father is such a motherfucker."

3.) "Billy, you haven't showered AGAIN, you motherfucker?!"
by iNFAMOUS RiCK March 12, 2005
 
27.
1. Someone who has most likely never fucked a mother, or if he has, it was a coincidence.
You're such a motherfucker.

How did you know?
by philpee July 10, 2008
 
28.
Pretty much meaningless insult. Used by alot of people but doesn;t really have any impact anymore since it's used so much.
use your imagination people you can pretty much put it in any sentence.
by rotten ralph July 27, 2004