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15.
It means 'most definately'
Q. "will you make it tonight? "
A. "mosdef "
by mitta lee-alle "hannah" August 11, 2010
 
1.
a fly MC, often apperaring alongside Talib Kweli, The Roots, or Common
mos def is one ill nigga, son
by Ponyboy August 03, 2003
 
2.
Slang for 'most definitely'
"Wan' a cig, man? "Mos' def!"
by David Allison August 21, 2003
 
3.
A man who can not only act with 5 star ability, but can also create some of the best shit out on recording ever.
Mos Def yet an actor of decent fame still keeps his hip-hop true.
by Paul October 02, 2003
 
4.
1.: A slang term for "most definitely."
2.: A rapper.
3.: Deaf - this useage is the least common, mostly by people who didn't understand it in the first place or mispronounced.
1.: "Am I going to the party? Mos def!"
2.: "Mos Def is one of the best rappers of our time."
3.: "After that concert, they're mos def."
by Gillian January 04, 2005
 
5.
Mos Def is many things. In everyday lingo, Mos def is an abbreviation that can mean "Most definitely"(1) wich originated from the ghetto but like every other gansta term has evolved inti something widely used by young and filthy rcih white kids.

Mos Def in the music and film industry is the pseudonym of Dante Smith(2). Quasi legendary emcee who's soulfoul approach to hip hop and unique style has made him one of hip hops heavy hitters. He and Talib Kweli are known to collaborate alot, even making Black Star. Mos Def is also a pretty good actor who appeared in the remake of "The Italian Job" and the still in production "The Hitchikers Guide to the Galaxy".

Last a probably least, Mos Def is a brand of urban clothing(3). Most of they're stuff is pretty basic, but pretty cool. Hell, I'd pay for a sweatshirt that says "Mos Def"

Last and probably least,
1-Crack Peddler: "HEY BITCH! You wanna suck my cock for a crack rock?"
Crack Whore:"Mos def!"

2-Man Mos Def is ill, but he was really pushing his luck with his newest album.

3-Guy 1:Hey look, is that a "Mos Def" brand sweatshirt?

Guy 2: *Looking at sweatshirt clearly labeled "MOS DEF"* man, you're lucky I dont have my trusty 2 by four to beat yo ass.
by mrpopenfresh March 05, 2005
 
6.
A poet and a great MC. Though his acting in the Alicia Keys video not so great. Check him out.
The mighty Mos Def, him and Kweli make a dynamic Duo.


They got Biggie and 2pac/
Too much violence in hip hop/
by Mos Def And Kweli are Blackstar February 25, 2005
 
7.
mos def a.k.a Black Dante a.k.a Dante Smith is an artist who shows plenty talents in singing,emceeing,and acting.
did u hear "the new danger" by mos def?
by kaya April 06, 2005