Top Definition
1. While the word's components imply that the subject would be a mother-fucking slut, the term mofoslut depicts the image of one who has made a mistake, or provided some trivial disappointment yet is still loved

(established in CSH, NY 2009)
Rachel: Thanks for not calling me!
Kim: I know, I know I'm a mofoslut.

Gabby:Can you come to my party?
Alexa:No, sorry!
Gabby:Wow, mofoslut.
by RCamps February 02, 2010

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