Top Definition
Michigan syndrome, as we have come to call it, is the "disease" that inflicts girls in michigan. Whenever we visit Lake Michigan, on the beach, there are hot girls everywhere, but they are with their ugly/wussy/dorky boyfriends. Whenever you see a hot chick with a guy who doesnt belong with her, that is michigan syndrome
"Dude, did you see that chick?"
"Yeah, she was hot, but judging from that guy she was with, she definitely has a case of the michigan syndrome"
by BSUprotege June 29, 2004

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