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1.
To be high on marijuana. Marijuana helps glaucoma, and chemotherapy so it's a medicine. It's just a more proper way of saying high.
jose- "Damnnnnnnnnnnnn, he is high!"

pete & patrick "Nah man, He's just medicated"
by That boy pete May 18, 2009
 
2.
To feel good no matter what kind of drug you are on. usually prescription drugs.
Ahhhhhh! man i feel nice and medicated.
by empower February 09, 2010