Top Definition
from "me cago de risa" in spanish meaning "i am laughing so hard i shit myself"
bob: no mames that is soo funny!!
jose: i know! mcdr!
by Maribel Viscarra June 28, 2008
1 more definition
9 Words related to mcdr
it's LMAO but in region 4. MCDR = me cago de risa.
jajajajjaa, mcdr.
by pablokenfold December 02, 2009

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