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1.
From Spanish.

Much, Really Much, More.

It's used to describe a great quantity of something, or enfatize something.
Es Mazo de fuerte! ( Es Muy Fuerte! ) --> It's Really Stroger!
Habia Mazo de Gente ( Habia Mucha Gente ) --> There Where Too many People
by ImGoingBlind April 09, 2006
 
2.
A James Brown band member.
"Hey, Mazo play dat again!"
by Shai66 November 28, 2007