Top Definition
A common affliction in South India, named after students attending schools in the city of Manipal. It is an acquired syndrome characterized by poor health, dementia, depression, laziness, copious ingestion of any available substance (alcohol to vitamins), avoidance of normal adult life activities. Individuals suffering from the syndrome grow backwards mentally and physically. The only known cure is leaving the city with a degree, which is actually a pristine, vividly green, and beautiful tropical town. Supportive therapy involves abstinence and exercise.
That dudes had Manipal syndrome since '98 and its slowly eating away at his brain.
by whathappenedtothatbird September 07, 2011

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