2. An extreme case of acne. Individuals with Manion Acne are typically reviled by God and should be avoided; exposure to pus excreted from the acne of these individuals can cause syphilis, contamination of the soul, impotence, and blindness.
3. A foul smelling creature.
v. Did you hear Billy's going to prison? Apparently he manioned his 8 year old sister.
2. Stay away from Mike, he's got bad case of manion.
3. Jesus, I bet you could smell that manion from outer space.