look up any word, like dirty sanchez:
 
1.
Guy who gets what he pleases, and can speak to bitches smoother then smooth peanut butter, a baby's ass, or even a shaved.......................head
Dom: Yo, did you see Mancini walk up to those girls. I wish I could do that!
Walko: Yea, hes cool. I wish I was cool like him, and not a tool.
by F G-town and P-boro June 19, 2007
 
2.
A set of summer shorts with a pattern not unlike a picnic blanket. Individual preferences include, but are not limited to: Plaid or Alternating of contrasting colored solid squares. Spotting someone wearing "Mancinis" is a clear indicator that summer has arrived. They are commonly seen at lakefronts, on camping trips or visiting newly born babies. One who chooses to wear "Mancinis" will often experience feelings of joy, drunkenness, and the warmth associated with being around good friends. Also commonly known as "Picnic Pants", The term "Mancini" is reserved for those of a higher social standing and ultimately more self respect.
Scenerio 1
Boy: "Why wont you go out with me?"
Girl: "You have no style and don't know how to party"
Boy: "I'm heading over to Bob's Stores to pick up a pair of Mancinis"
Girl: "Really? Lets make love!!"

Scenerio 2
Prince William: "What should I wear on our honeymoon?"
Catherine Middleton: "Mancinis of course"

Fact:
"Every time a bell rings"...Chuck Norris kills someone with a roundhouse kick to the face and then wipes his victims blood on his new "Mancinis"
by Joman416 June 06, 2011
 
3.
Extreme case of constipation, e.g. Victor Manicini in the novel Choke who got an anal bead stuck up his ass and couldn't poop.
I had a bad case of the Mancinis last week but I'm fine right now.
by Tyscyth November 13, 2010