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1.
1. The point at which something goes beyond the realm of "mad stupid" and reaches the point of pure silliness and the non-sensical. Can refer to people, situations, or ideas.

2. Expressing disbelief that someone or something could be so very, very stupid.
Laine: That's mad stupes.

No further context is necessary.
by alwaysontwitter May 01, 2011