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1.
used in the opposite situation as win, usually when something disappointing has been mentioned
A: I think I just failed a math test
B: Lose.

A: Fuck, Starcraft II doesnt come out for another year.
B: Double Lose.
by vx14 November 30, 2007
51 33
 
2.
same as the verb, but treated as a noun.
What a lose, I just dropped my ice cream cone.
by Lex Luther Vandross March 22, 2004
43 42
 
3.
1) Noun: an undesirable action; a snitch; a bothersome individual

2) Adjective: used to describe something unfavorable

3) Verb: to do something that is seen as wrong or obnoxious
My bitch ass brother is such a lose; he tells on me for everything.

School is a huge lose.

Why would you do that? That loses.
by H Town Blizzard November 15, 2007
16 17
 
4.
To break up with a girl if she ain't doin anythin with you.
"I'm gonna lose this bitch if she don't give out."
by footballstud580 April 03, 2004
56 57
 
5.
to leave or go out
I'm lose
by the infamous chocolate October 23, 2003
10 48