look up any word, like the eiffel tower:
Like the insult grow a pair, only said to a girl acting particularly manly or that looks like a man. Also used to just make one mad.
Jane: Shut up Bob you know I'm strong and can beat up guys!
Bill: Wow Jane, how about you lose a pair and act like a girl!

Bob: Hey Kate! Lose a pair!
by Johnny Locke April 19, 2010