Top Definition
Based on the fantastic Loony Tune cartoons of the 1940's & '50's that featured Bugs Bunny, Daffy Duck, and a host of other memorable cartoon characters, many featuring the truly schizoid voices of Mel Blank. Thus a loony tune is a take-off on these cartoon characters - meaning a person's out of touch in a loopy, goofy, sarcastic kind of way - flaky but right on too.
"Did you see Bruno at the party last night?"
"I saw him. Since he started that smack thing, guy's a fucking loony tune. Dive off the third-floor motel balcony into the pool & split the take for someone passing the hat or taking bets."
"Bruno, man. I saw him fold a coat hanger & put it in his fucking mouth in 60 seconds. Forty bucks take home, tax free. Loony tune, man. Tres unstable."
by thunderbeing September 09, 2009

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A condition in which a person is psychotic.
Jack is strictly loony tunes since Heidi ran off with the postman.
by eViL pOp TaRt August 31, 2005

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