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1.
Crazy female. Typically used as an adjective
Mira ese loca puta

Look at that crazy bitch
by h0mi May 03, 2004
 
2.
Loca could be in different wayz. There's loca like crazy, Loca like a clique name, loca like a fly female and loca like a bitch.
"'ta loca esa si quiere salir con el"
"Oye, s'all about the L.o.c.a.s!"
"Mira esa loca ova there..Damn1"
"La loca esa is gettin up in my face and talkin sh!t bout my outfit"
by Laura January 03, 2004
 
3.
a noun used for a gay guy;synonym to marica(marika)
Ese es una loca.
That guy is a loca.
by ColombianitaNJSC April 18, 2005
 
4.
Immature girl that plays up to guys offering them 'cyber sex' in order to get them on her side. Generally a bitch too.
meet me on aim loca ;)
by obeliskone March 05, 2008