Justin: "Stop everything you are doing!! Think about ME for 3 secs...1...2....3! You just experienced the best 3 secs of your life."

Donna: Thanks Justin, I'm LMSO!
by donna/justin October 12, 2009
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When Phal broke his leg we were laughing our socks off...thats still no excuse to lose to George 3 games in a row though.
by GEO July 22, 2003
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Laughing my shiz out
Person 1: you’re cute

Person 69: Lmso
Person 1: u said it wrong

Person 69: no I didn’t
by FreshestAvocado December 10, 2018
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"Laugh my shit(s) out."
Person 1: I collect my boogers in a Ziplock bag.
Person 2: LMSO!
by cheeeeezystix March 20, 2010
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Bob~ "Hey dude, remember that funny thing i did last night?"

Jack~ "yeah, LMSO"
by A7Xrules112 January 7, 2011
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GUY 1 (after seeing a funny picture): LMSO! …laughing my shirt off.

GUY 2: Too bad you're not a buxom female.
by themagicalnegro May 19, 2010
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Laughing my shirt off - a variation of LMAO. Often followed up by "AFITAC!" "and feeding it to a cow!" as popularized by the British gangsta-gypsy-rock band Larrikin Love's song On Sussex Downs.
Ed is so Rubbish that I was LMSO AFITAC!
by K8 'n' Sandy January 13, 2007
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