Much the same as "living shit", "the bejesus", or "the devil"; for example, when you're beating the living shit out of something.
Andrew went on the rampage at work this morning when the copier spit toner all over him -- he literally beat the living tweedle out of the poor, defenseless, helpless copy machine!

Topher was so fond of his new R/C piloting skills; he flew the living tweedle out of his Cessna 182 R/C airplane at the park over the weekend.
by Telephony July 27, 2012

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