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1.
lead singer of the yeah yeah yeahs. an extroverted performer, a good lyricist, and a wearer of crazy stage get-ups. known for swilling beer and spitting it out at the audience.
we need more girls like karen o.
by cock123456789 December 31, 2005
269 53
 
2.
lead singer of the new york punk band the Yeah Yeah Yeahs. Probably the coolest women on the planet-known for performing weird sexual acts with the microphone when performing live, and dressing up in ridiculous costumes, and drinking loads of booze.
guy 1: hey, did you see karen o at that concert last night
guy 2: No, why?
guy 1: because she got completely wasted and fell off the stage.
by admmad March 27, 2008
68 20
 
3.
lead singer of the new york punk band the Yeah Yeah Yeahs. Probably the coolest women on the planet-known for performing weird sexual acts with the microphone when performing live, and dressing up in ridiculous costumes, and drinking loads of booze.
guy 1: hey, did you see karen o at that concert last night
guy 2: No, why?
guy 1: because she got completely wasted and fell off the stage.
by admmad March 27, 2008
26 15