Top Definition
1. the nausea commonly experienced by narcotics users after the drug begins to wear off.

2. withdrawals caused by using narcotics, similar to the symptoms of the flu.
+ I'm junk sick from all the percocet I railed last night.

+ I feel all shaky and horrible, like I'm gonna puke. I must be junk sick again.

+ you must be sick from all that junk you've been shooting.
by cafebrulot November 13, 2006

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