A term used on Craigslist to denote a posting in a discussion forum that was so vile, so nasty, so rude, so off-topic, or, simply, so freakin' DUMB that it needed to be removed. Such posts are sent to the "Isle of Misfit Threads" in forum 1047.
"Keep posting here, Staff has Isled your posts...soon you'll be missing a handle!"
A girl with the name Istene is a girl one can't go wrong with. A bomb body, high flying, curly headed, blond with the most enthusiasm ever to walk the earth, are topical traits of a girl with a name some say to be forged in stone by Excalibur 500 years ago. She therefor has the power and will to save this world though her god given powers as well as the Heart of a Blue Whale and the brain and logic of Einstein as an extra bonus. This name is truly remarkable; one of a kind, as Zeus would say!