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1.
When a single male with no children dates a girl that already has kids.
Fernando: "Did you see Joel is dating that girl with a 10 year old son?"
DeeJay: "Whoa. Insta-fam!"
by DeeJayMC December 19, 2006
 
2.
A term used to refer to your followers on Instagram.
'Did you see that iconic photo I took yesterday of my patented gourmet beans on toast recipe?'
'Fuck that shit, I wouldn't join your Instafam if you payed me bruv'

'Finally reached 20,000 followers, big luv to all my Instafam!'
by keiranmerrick August 13, 2014
 
3.
When one becomes so attached to instagram where it becomes part of your life much like your family
Nigga u stay on intsagram like...its your instafam now
by milboinks December 24, 2012
 
4.
When a person marries someone who already has children from a previous relationship, usually said of a single, never married man. Single, never married men tend to use this term in a derogatory manner until it happens to them.

This may be considered an alternate definition of 'instafamily' as well.
Bob's new wife has three kids from her first marriage. Bob has an instafam- just add daddy.
by dalaggie January 30, 2008