Something in your mind that keeps you from doing something that you really want to do/happen. Often the reason why a man won't make a move on a lady, it makes him unconfident and hesitant. The way to get rid of this inhibiton or inhibitions is to drink. That is one of the benfits to alcohol, it makes you more open and free to do what you want.
After a few drinks, Ryan easily made a move on Katy and ended up getting the goodness.