Top Definition
Positive thinking regarding one's immune system especially when one's faced with probable or widespread contagion.
Leo: Are you sure you want to come over for dinner? My sister has chicken pox, my dad has the flu, and I'm still getting over the clap.
Kay: Sure, I'm not worried, I never get sick.
Leo: Wow babe, that's some serious immuno-optimism.
by schulwitz February 15, 2012

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