A state in which you are extremely annoyed by other humans and their unseemly activities, despite being human yourself. Very aware and intelligent individuals who aren't "people persons" seem to be most prone to being humannoyed. This state is usually transient, otherwise it may signal some sort of antisocial personality disorder when very prolonged. Note this is usually a state of disdain, not aggression.
I don't go out on Black Friday," Jane said, "because if I do I will become intensely humannoyed by all of those grabby, greedy fools and their terrible spawn. I'm not a consummate misanthrope, but humans sure are a bane to this planet and my sanity sometimes.