Top Definition
noun - a typical male "illness" in which the cute male is very sweet and caring at first but then turns and is a complete asshole.
Angie - Man, Jeff used to be really cool and sweet and loving, but now it's like I don't even know him anymore.

Julie - Yeah, he sounds like he's got himself the Hott Guy Syndrome.
by Daygona November 05, 2007
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