When you have sex with a really good looking guy "hot" man and you are laying on your back... it refers to the knot that forms in your hair on the back of your head.
If you had sex doggy style you would have a hotknot in your bangs if your head was smashed into the pillow.
by ViolaValhalla and Hot January 06, 2009
Inflammation and burning of the Anus that occurs after digesting particularly spicy foods such as jalapenos or wasabi.
"Ive got a mean case of hot knot, must have been the wasabi I ate last night."
by Hot Knot October 06, 2006