look up any word, like dirty sanchez:
 
1.
1. The paradoxical state of being both a homosexual (homo) and a motherfucker (mofo). One who is both latently gay and depraved enough to have sex with his own mother.

2. A devoted male fan of rock group Good Charlotte.
"What a homofo!"

"I can't believe Dan could be such a homofo!"

"You goddamn homofo."
by Setkino September 21, 2007
 
2.
Jus something to add on in insulting someone. Instead of calling im/her a ho-mo or a mo-fo you put u ho-mo-fo (homosexual mother fucker)
Alfie - u homo! James - u mofo! Roger & Haz - u ho-mo-fo's!!!!
by Roger & Harry October 23, 2007
 
3.
Hot Mother Fucker
Girl 1: DAMN look at Will today! hes looking fineee
Girl 2: oh yeah hes a homofo
by Will the homofo November 10, 2010
 
4.
Homsexual and a mofo at the same time
You're one big homofo
by virushark October 14, 2003
 
5.
combination between homo and mofo.... used to describe those that are being complete douche bags..
person 1-"OMG OMG OMG OMG GUESS WHATTT?!?!?"
person 2- what?
person 1- "UR MOM SAYS WHAT!!"
person 2- shut the FFFFFF....ront door, ur such a homofo...
by A&F model October 25, 2006