The term "homie" was started by Mexican-Americans, most commonly in East Los Angeles, though, of course, the credit givin for the term goes out mostly to African-Americans. The term derrives from Homeboy, and was shortened down to just "Homes" or sometimes spelled "holmes", which is another Mexican-American term, commonly used in California. Rapper Biggy Smalls has used the term homes/Holmes commonly.
Person 1: Whats happenning homie
Person 1: just chilling homes.
by Eddie.P March 24, 2007

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Contrary to popular belief, it was the Chicanos aka Mexican-American Pachuos of Los Angeles who created words such as Homie, Homeboy, and Homes which were all derived from their slang known as "Calo". However, Blacks adopted it and there's people who still think they created it just like they think they created Lowriders and call California "Cali" when the Pachucos did that.
Pachuco #1: What's happenin homie?

Pachuco #2: Just kickin it homes.
by rob-g April 13, 2007

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can also be short term for homer (simpsons)
marge calls him homie..
Marge: aww, my poor homie...
by private1 September 26, 2006

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friend in ghetto language
perhaps a close friend or trusted pal
yo homie, come pass that rock to yo main homeboy aiiiiight cheeeea
by jigga main 11 May 20, 2003

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1. table partner (in school)

2. lab partner
Mrs. Martin: For this lab, you will work with your homie and another pair of homies.
Homie #1: Let's work with those homies, homie.
Homie#2: Yes, those look like good homies to work with.
by silly teenage boy February 12, 2017

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Homies are the people who are bestfriends , in a way . Usually referred to as "my nigga" or my "ride or die" . Homies will always be there for that one person , no matter what . Even if they have to do something crazy .
Person 1: hey ! Do you see Chris and Olivia over there , just chilling ?
Person 2: yeah why ?
Person 1: I wish our relationship was like theirs !
Person 2: why ??
Person 1: cause they're homies !
by HisHomie September 07, 2014

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YOUR HOME DOG
ME: WAS SUP HOMIE
DOG: WOOFFF!!!!!
ME: I DON'T THINK IM DOING THIS RIGHT
(?GET IT?)
by AAAAAAAAAABBBBBBBBBBBCCCCCCCCM December 03, 2010

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