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Contrary to popular belief, homeboy along with homie were both created by Chicano aka Mexican American Pachucos from the word "Hombre" which is spanish for "man". It all derived from the slang they used known as "Calo".
Chuco #1: What's happenin homie??

Chuco #2: Just kickin it with my homeboy.
by rob-g April 13, 2007
212 177
closest friend
What it is, homeboy?
by D P September 24, 2002
1114 328
A close friend.

Originally used among transplanted African-Americans with Southern roots to refer to and aid in the assimilation of someone who might have directly migrated from a common Southern home town or is otherwise well known to the person using the term.

Used to establish a mutual relationship between the invidividual using the term, the person described by it, and a third person.
That's my homeboy Carl.
by Glenn November 18, 2004
797 337
Guy to chill with. long-time friend.
Jesus is my homeboy!
by ali bee September 04, 2004
580 299
one of your peeps -- a good friend. derived from the spanish ''homebre''
que pasa home boy?
by Anonymous July 10, 2002
369 146
The epitome of a friend. Somebody you kick it with. A person who always has your back. You can't go through life without a homeboy. It's hard to have more than one, because they're one in a million.
You ain't shit without your homeboy - Tupac Shakur
by Poopdeck222 March 28, 2007
393 198
A vessel for spreading news, especially in the case of perps snatchin' yo people up, tryin' to rape 'em.
Run and tell THAT, HOMEBOY!
by RAKER69 August 23, 2010
331 189
A turm that came From American Gi's In world war two To Idenity other soliders for their home towns,cities & states. It is more commonly used now as a turm To mean a friend from the neighborhood or a gang member
- That kid joe is Ok he's a home boy from st louie
by NLR718 June 03, 2006
176 79